Induction of apoptosis or cell cycle arrest by two human wildtype variants of the p53 protein
The human wildtype p53 tumor suppressor gene is found in two different forms, p53 Arginine and p53 Proline. This difference results in a substitution of a proline for an arginine at codon 72 producing the polymorphism. Knowing that apoptosis and cell cycle arrest are the two main functions of p53, t...
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| Format: | Others |
| Language: | en |
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McGill University
1999
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=30337 |