Experimental studies on complete deprivation of arterial supply to the liver, with special reference to welch bacillus infection

It has been known for many years that complete ligation of the arterial supply to the liver was rapidly fatal in several mammalian species. Considerable speculation as to the pathological changes and mechanism of death have failed to uncover a satisfactory explanation. In general, if the portal vein...

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Bibliographic Details
Main Author: Chau, Andrew Y.
Other Authors: Webster, D. (Supervisor)
Format: Others
Language:en
Published: McGill University 1950
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Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=122679
Description
Summary:It has been known for many years that complete ligation of the arterial supply to the liver was rapidly fatal in several mammalian species. Considerable speculation as to the pathological changes and mechanism of death have failed to uncover a satisfactory explanation. In general, if the portal vein is left intact, arterial ligation alone does not produce definite infarction, but a focal or massive necrosis usually appears within twenty-four hours. In 1949 it was reported by Markowitz, Rappaport and Scott that dogs which were treated with penicillin were able to survive complete hepatic arterial ligation.