Vorinostat potentiates vesicular stomatitis virus oncolysis in prostate cancer cells by modulating autophagy in an NF-kB dependent manner
Vesicular stomatitis virus (VSV) replication and oncolytic potential is reversibly stimulated in combination with epigenetic modulators such as the histone deacetylase inhibitor (HDI) Vorinostat (SAHA). Based on this reversible effect of Vorinostat on viral oncolysis, we reasoned that critical host...
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| Format: | Others |
| Language: | en |
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McGill University
2014
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121210 |