Spinal opioid-adrenergic analgesic interactions: mechanistic insights on the role of the delta opioid and the alpha2A adrenergic receptors
Opioid and α2-adrenergic receptor (α2AR) ligands are both analgesic when administered spinally and show a clinically beneficial synergistic interaction in the treatment of pain when co-administered. The µ- and δ-opioid receptors (MOR and DOR respectively) and the α2AARs have been shown to be capable...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | en |
| Published: |
McGill University
2014
|
| Subjects: | |
| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=121147 |