The role of the p66-Shc adapter protein in mammary tumourigenesis

The ShcA adaptor protein is a key signaling molecule in the regulation of survival, angiogenesis, immune suppression and metastasis in breast cancer cells. The mammalian ShcA gene encodes three isoforms which are produced through alternative translation initiation (p46Shc, p52Shc) or different promo...

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Bibliographic Details
Main Author: Podmore, Lauren
Other Authors: Giuseppina Ursini-Siegel (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2013
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119690