The role of the p66-Shc adapter protein in mammary tumourigenesis
The ShcA adaptor protein is a key signaling molecule in the regulation of survival, angiogenesis, immune suppression and metastasis in breast cancer cells. The mammalian ShcA gene encodes three isoforms which are produced through alternative translation initiation (p46Shc, p52Shc) or different promo...
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Format: | Others |
Language: | en |
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McGill University
2013
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=119690 |