Broad-spectrum inhibition of virus infectivity by an RNA agonist of the RIG-I Pathway
The cytosolic antiviral pathway is stimulated during virus infection by interaction between the RIG-I like receptors and viral RNA structures that contain short hairpin dsRNA and 5' triphosphate (5'ppp) terminal. In the present study, RNA-based agonists of RIG-I, derived from the 5' a...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116951 |