Novel role for αNAC as a scaffold protein that differentially recruits HDAC-containing corepressor complexes for the repression of Integrin-B6
The nascent-polypeptide-associated complex and coactivator-alpha (αNAC) is a subunit of a cytosolic heterodimer that binds to ribosomes and newly synthesized polypeptides in a chaperone-like manner. In the nucleus, αNAC acts as a transcriptional coregulator that can potentiate the expression of the...
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| Format: | Others |
| Language: | en |
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McGill University
2013
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114488 |