Angiotensin blood levels in man.

• Main Author: Chretien, Michel.
• Other Authors: Genest, J. (Supervisor)
• Format: Others
• Language: en
• Published: McGill University 1962
• Subjects: Investigative Medicine.
• Online Access: http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=113600

The problem of human arterial hypertension has been one of the most debated subjects in modern medicine. Many groups of investigators and clinicians have been interested in its etiology, its physiopathology and its treatment. The first suggestion that the kidneys might be responsible for this disease entity came from Richard Bright in 1836,and it was the result of a remarkable clinical acumen. In 1898, Tigerstedt and Bergman injected crude saline extract of rabbit kidney into anesthetized rabbits and observed a prolonged rise in blood pressure; they named this unknown pressor principle “rennin”.