The influence of a mold product on the antigenicity of staphylococcal toxin: further studies.
In 1947 D.G. Denton (Murray, Denton, Stevenson, and Diena, 1957) isolated a mold, later identified as Penicillium cyaneo-fulvum, and demonstrated that it produced in culture a substance which neutralized staphylococcal alpha-haemolysin. In subsequent work on this toxin-neutralizing agent, Diena (195...
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| Format: | Others |
| Language: | en |
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McGill University
1957
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111345 |
| Summary: | In 1947 D.G. Denton (Murray, Denton, Stevenson, and Diena, 1957) isolated a mold, later identified as Penicillium cyaneo-fulvum, and demonstrated that it produced in culture a substance which neutralized staphylococcal alpha-haemolysin. In subsequent work on this toxin-neutralizing agent, Diena (1954 and 1956) developed a method of purifying the toxin-neutralizing substance and established that it neutralized a wide spectrum of bacterial toxins. The toxin neutralizing substance derived from culture filtrates of P. cyaneo-fulvum has been designated Noxiversin. The purpose of this investigation was to study some of the characteristics of the neutralization of staphylococcal alphahaemolysin by Noxiversin. |
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