Biological Studies on Treponemata.

• Main Author: Speers, Robert.
• Other Authors: (Supervisor)
• Format: Others
• Language: en
• Published: McGill University 1957
• Subjects: Bacteriology and Immunology.
• Online Access: http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=111333

This investigation was originally undertaken because it offered a challenge to attempt the solution of a biological connundrum which has existed for more than half a century. As will be seen later, in the review of the literature, T. pallidum has yet to be grown in vitro (with retention of its pathogenicity for experimental animals) and this fact alone would be enough to stimulate an investigation of the fundamental biological properties of this organism. At the same time, the successful in vitro cultivation of T. pallidum would undoubtedly lead to the development of a stable specific antigen and have far reaching effects in syphilis research. [...]