New synthesis of papaveraldine, isoquinoline and related open-chain compounds.

In the course of a series of investigations in these laboratories on the chemistry of vanillin, attempts were made to improve the synthesis from it of the opium alkaloid papaverine. This alkaloid finds use in medicine as one of a group of spasmolytic drugs with a paralyzing action on the smooth musc...

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Bibliographic Details
Main Author: Frank, Arlen. W.
Other Authors: Purves, C. (Supervisor)
Format: Others
Language:en
Published: McGill University 1954
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=109776
Description
Summary:In the course of a series of investigations in these laboratories on the chemistry of vanillin, attempts were made to improve the synthesis from it of the opium alkaloid papaverine. This alkaloid finds use in medicine as one of a group of spasmolytic drugs with a paralyzing action on the smooth muscles of the intestines and blood vessels. Unlike some of the other opium alkaloids, papaverine is neither narcotic nor habit-forming.