Perturbing the epigenome: effects of folate pathway disruptions and combination chemotherapy treatment on male germ cells

Healthy gametes are essential for the survival of the species. Epigenetic marks, including DNA methylation, are crucial components of proper germ cell development and have been shown to be important for fertility and embryo development. DNA methylation patterns in male germ cells are initially acq...

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Bibliographic Details
Main Author: Chan, Donovan
Other Authors: Jacquetta M Trasler (Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107681