The acquisition, dynamics, and perturbation of DNA methylation in the prenatal and early postnatal male germline

DNA methylation is an epigenetic modification that is essential for germline and embryo development. DNA methylation establishment occurs in the germline in a gender and site specific manner through the action of DNA cytosine-5-methyltransferase (DNMT) enzymes. Spermatozoa have been shown to have a...

Full description

Bibliographic Details
Main Author: Niles, Kirsten Marijke
Other Authors: Jacquetta M Trasler (Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=107573