Design and synthesis of A-ring/seco B-ring vitamin D analogues

A new series of vitamin D analogs were synthesized with a saturated seco B-ring and several potential aromatic A-ring mimics. These new A-ring/seco B-ring analogs examine the possibility of forming positive electrostatic interactions in the seco B-ring portion of the vitamin D nuclear receptor, the...

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Bibliographic Details
Main Author: Lacroix, Jean-François
Other Authors: James L Gleason (Internal/Supervisor)
Format: Others
Language:en
Published: McGill University 2012
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106520