Interrelationship between tetherin-mediated restriction and its Vpu-mediated antagonism in HIV-1 cell-to-cell spread and the potential to develop Vpu as an antiviral target
This doctoral thesis comprises three parts. The first two parts (Chapter 2 and 3) define the role of the host cell restriction factor tetherin in restriction of HIV-1 cell-to-cell spread. These chapters also characterize the tetherin-inducible cell line Sup-T1 that was used in Chapter 4 to investiga...
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| Format: | Others |
| Language: | en |
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McGill University
2011
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104781 |