Risks of aprotinin in cardiac surgery: a Bayesian evidence synthesis of randomized and observational studies

Background: Aprotinin, a serine protease inhibitor, was approved by the FDA in 1993 for use in patients at an increased risk of blood loss during cardiac surgery. Due to its mechanism of action, aprotinin has a potential for increased risks of thrombotic and renal adverse events. Since 2006, finding...

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Bibliographic Details
Main Author: Hutton, Brian
Other Authors: Dean Fergusson (Supervisor2)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=104485

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