Mechanisms employed by HIV and SIV to overcome the antiviral activity of BST-2/tetherin

BST-2 (tetherin/CD317/HM1.24) is an interferon-inducible cellular factor that is able to retain fully formed viral particles at the cell surface. This effectively prevents the release of a wide range of viruses including HIV-1 and SIV. Viruses in turn have evolved mechanisms to overcome this restric...

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Bibliographic Details
Main Author: Cheng, Vicky
Other Authors: Chen Liang (Supervisor)
Format: Others
Language:en
Published: McGill University 2011
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=103595