Structural determinants of protein tyrosine phosphatase 1B inhibition
Inhibition of Protein Tyrosine Phosphatase 1B (PTP1B) has been proposed as a novel therapy to treat type 2 diabetes by sensitising the patients to the effect of insulin while protecting them against diet-induced obesity. A mutant screen in yeast was devised to facilitate the identification of residu...
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2005
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| Online Access: | http://spectrum.library.concordia.ca/8294/1/Montalibet_2005.pdf Montalibet, Jacqueline <http://spectrum.library.concordia.ca/view/creators/Montalibet=3AJacqueline=3A=3A.html> (2005) Structural determinants of protein tyrosine phosphatase 1B inhibition. PhD thesis, Concordia University. |