Characterization of temperature-sensitivity and its intragenic suppression in Saccharomyces cerevisiae tRNA nucleotidyltransferase mutants
ATP:CTP-specific tRNA nucleotidyltransferase enzymes catalyze the stepwise addition of one CMP, a second CMP, and finally an AMP as needed to generate the functional 3’ termini of tRNA molecules. The following work concerns the structural and functional characterization of a temperature-sensitive va...
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