The stereoselective synthesis of a novel aromatic peptide nucleic acid (APNA) oligomer
The synthesis of the thymine derivative (S)-50, was achieved in high enantiomeric purity (98% ee). The (R) enhanced enantiomer was also synthesized with moderate enantiomeric purity (46% ee). This acyclic pyrimidine analog ((S)-50) is a useful building block for the synthesis of a novel class of oli...
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1997
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| Online Access: | http://spectrum.library.concordia.ca/225/1/MQ25983.pdf Lunetta, Jacqueline F <http://spectrum.library.concordia.ca/view/creators/Lunetta=3AJacqueline_F=3A=3A.html> (1997) The stereoselective synthesis of a novel aromatic peptide nucleic acid (APNA) oligomer. Masters thesis, Concordia University. |