Long-term potentiation in the sensorimotor cortex of the awake rat is effectively induced by theta-patterned stimulation
The neocortex of awake animals is resistant to the induction of long-term synaptic potentiation (LTP). To determine if intense stimulation patterned after the theta (4-12 Hz) electroencephalographic (EEG) rhythm may be effective in inducing synaptic plasticity in the sensorimotor cortex, LTP inducti...
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