Alternative splicing of Lymnaea Cav3 and NALCN ion channel genes serves to alter biophysical properties, membrane expression, and ion selectivity

Evidence is presented that Lymnaea contains homologues for mammalian Cav3 and NALCN 4-domain ion channels, which retain key amino acid sequence motifs that differentiate these channels from other 4-domain types. Molecular cloning and heterologous expression of the first invertebrate Cav3 channel cDN...

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Bibliographic Details
Main Author: Senatore, Adriano
Language:en
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10012/6926