Assessment of the cell cycle proteins Cdc7 and PCNA as markers of colon carcinogenesis in obese and lean rats
Obesity increases the risk of colon cancer as well as the expression of many cancer markers, ostensibly due to the interaction between insulin resistance and adipocyte production of hormones, mitogens and cytokines which collaborate to enhance proliferation signaling and impair the DNA damage respon...
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| Language: | en |
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2009
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| Online Access: | http://hdl.handle.net/10012/4853 |