Pharmacogenetic Analysis of Dopamine and Glutamate Receptor Gene Polymorphisms and Clinical Response to Clozapine in Patients wtih Schizophrenia
Interpatient variability in clinical response to antipsychotics (AP) is observed in the treatment of schizophrenia (SCZ) with evidence to support a genetic basis for this phenomenon. Dysfunction in the dopaminergic (DA) system as well as the glutamatergic (GLU) system have both been implicated in t...
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| Language: | en_ca |
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2014
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| Online Access: | http://hdl.handle.net/1807/44116 |