The Role of GSK-3 in Mammary Gland Development and Oncogenesis
Glycogen synthase kinase-3 (GSK-3) alpha and beta are central regulators of key developmental pathways, including Wnt, Hedgehog and Notch, which control stem cell activities and cellular differentiation. Both forms of GSK-3 are also regulated by receptor tyrosine kinases via the PI3K/Akt growth-prom...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/43532 |