Probing the Oligomeric Status of G Protein-Coupled Receptors by Forster Resonance Energy Transfer and Single-Particle Fluorescence

Much evidence indicates that G protein-coupled receptors can form oligomers, but the size and stability of those oligomers has not been well characterised. We used single-particle tracking (SPT) and Förster resonance energy transfer (FRET) to measure the oligomeric size of the M2 muscarinic receptor...

Full description

Bibliographic Details
Main Author: Strokach, Alexey
Other Authors: Wells, James W.
Language:en_ca
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/1807/42925