A Conserved Family of ER Proteins NLF Regulate the Na+ Leak Channel NCA/NALCN in Caenorhabditis elegans and Mus musculus
Neuronal excitability is controlled by multiple ion channels at the plasma membrane of neurons. Recently, the Na+ leak channel, NCA in C. elegans and NALCN in M. Musculus, has been identified as the molecular entity responsible for the background Na+ leak at rest in neurons. In this thesis, I show t...
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| Language: | en_ca |
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2013
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| Online Access: | http://hdl.handle.net/1807/42662 |