SATB2 is a Modulator of p63(alpha) in Cancer and Development

p63(alpha) belongs to the p53-family of proteins and has full-length (TA) as well as truncated ((delta)N) p63(alpha) isoforms. Previous studies have shown that TA and (delta)Np63(alpha) play multiple roles in cancer and development. In cancer, (delta)Np63(alpha)-mediated transcriptional repression...

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Bibliographic Details
Main Author: Chung, Jacky
Other Authors: Kaplan, David
Language:en_ca
Published: 2012
Subjects:
p63
Online Access:http://hdl.handle.net/1807/36209