Bayesian Methods for Genetic Association Studies

Bayesian Methods for Genetic Association Studies

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We develop statistical methods for tackling two important problems in genetic association studies. First, we propose a Bayesian approach to overcome the winner's curse in genetic studies. Second, we consider a Bayesian latent variable model for analyzing longitudinal family data with pleiotr...

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Bibliographic Details
Main Author: Xu, Lizhen
Other Authors: Craiu, Radu V.
Language:en_ca
Published: 2012
Subjects:
winner's curse
spike and slab prior
Hierarchical Bayes Model
Bayesian Model Averaging
Latent variable model
pleiotropy
genetic association studies
Markov chain Monte Carlo
path sampling
Bayesian inference
0463
Online Access:http://hdl.handle.net/1807/34972

Internet

http://hdl.handle.net/1807/34972

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