Association of Tissue Promoter Methylation Levels of APC, RASSF1A, CYP26A1, and TBX15 with Prostate Cancer Progression

Association of Tissue Promoter Methylation Levels of APC, RASSF1A, CYP26A1, and TBX15 with Prostate Cancer Progression

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Aberrant promoter methylation is known to silence tumor-suppressor genes in prostate cancer. Using a quantitative real-time PCR assay(MethyLight), I determined promoter methylation levels of APC, RASSF1A, CYP26A1 and TBX15 in 219 radical prostatectomies diagnosed between 1998-2001, examined their co...

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Bibliographic Details
Main Author: Liu, Li Yang
Other Authors: Bapat, Bharati
Language:en_ca
Published: 2012
Subjects:
DNA Methylation
Prostate Cancer
Epigenetic Mechanism
Progression
Biochemical Recurrence
0369
0307
Online Access:http://hdl.handle.net/1807/33724
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