The Role of the Ubiquitin Ligase Nedd4-1 in Skeletal Muscle Atrophy
Skeletal muscle (SM) atrophy complicates many illnesses, diminishing quality of life and increasing disease morbidity, health resource utilization and health care costs. In animal models of muscle atrophy, loss of SM mass results predominantly from ubiquitin-mediated proteolysis and ubiquitin ligase...
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Language: | en_ca |
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2012
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Online Access: | http://hdl.handle.net/1807/33472 |