Whole Transcriptome Analysis Reveals Established and Novel Associations with TMPRSS2:ERG Fusion in Prostate Cancer

Whole Transcriptome Analysis Reveals Established and Novel Associations with TMPRSS2:ERG Fusion in Prostate Cancer

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Shortcomings of current methods of prostate cancer detection draw attention to a need for improved biomarkers. The TMPRSS2:ERG gene fusion leads to the overexpression of ERG, an ETS family transcription factor, and is the most prevalent genetic lesion in prostate cancer, but its clinical utility rem...

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Bibliographic Details
Main Author: Chow, Anthony
Other Authors: Seth, Arun
Language:en_ca
Published: 2012
Subjects:
TMPRSS2:ERG
fusion gene
whole transcriptome analysis
RNA sequencing
prostate cancer
RhoGDIB
0307
Online Access:http://hdl.handle.net/1807/33381

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