Regulation of B Lymphopoiesis: The Role of IL-7, SOCS-1, Heparan Sulfate and CD19 in Mediating B Cell Development
B lymphopoiesis is regulated by cytokines, chemokines and cell surface proteins that initiate signal transduction pathways necessary for maturation to proceed. Many of these factors are expressed by cells in the surrounding bone marrow (BM) microenvironment, which also form the niches that support d...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32690 |