Regulation of Core Splicing Factors by Alternative Splicing and Nonsense-mediated mRNA Decay

The majority of human genes are transcribed into a precursor messenger RNA (pre-mRNA) that is processed to produce multiple mRNA variants through alternative splicing. Although alternative splicing is known for its role in generating proteomic diversity, it can also regulate gene expression by intro...

Full description

Bibliographic Details
Main Author: Saltzman, Arneet
Other Authors: Blencowe, Benjamin
Language:en_ca
Published: 2011
Online Access:http://hdl.handle.net/1807/31930