Characterizing the Role of a Novel F-actin Binding Protein in IRS1/PI3K Signaling and Glucose Uptake
Studies show that insulin induced activation and assembly of insulin receptor substrate-1 (IRS1) and phosphatidylinositol-3-kinase (PI3K), within remodelled actin structures is critical for GLUT4 translocation to the cell surface in muscle cells. This study identifies the F-actin binding protein, n...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/30127 |