Involvement of Nlrp5 in the Maintenance of Genome Integrity in Murine Oocytes
Nlrp5, a maternal-effect gene, is required for embryonic progression and female fertility in mice. Previous work indicated an age-related decline in Nlrp5 transcripts in murine oocytes. As maternal age is associated with increased spindle organization defects, studies in this thesis focused on the a...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29636 |