Molecular Mechanisms of Intracellular Apolipoprotein B100 Degradation

Apolipoprotein B100 (apoB), a necessary component of very low density lipoproteins, is overproduced in metabolic disorders such as type II diabetes, increasing the risk of atherosclerosis. ApoB production is regulated by intracellular degradation of the protein by proteasomes, ER-60-dependent degra...

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Bibliographic Details
Main Author: Rutledge, Angela
Other Authors: Adeli, Khosrow
Language:en_ca
Published: 2010
Online Access:http://hdl.handle.net/1807/26320