Cockayne Syndrome B is Required for Neural Precursor Self-renewal and Neuritegenesis after DNA Damage
Neural precursor cells self-renew and differentiate throughout development and in response to neural injury in the adult brain. The DNA damage response in NPCs has yet to be characterized. Patients with defective nucleotide excision repair (NER) demonstrate neurodegeneration dismyelination, and micr...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/25785 |