An Investigation of Nicotine Metabolism in Mice: The Impact of Pharmacological Inhibition and Genetic Influences on Nicotine Pharmacology
INTRODUCTION: Smoking is one of the single greatest causes of numerous preventable diseases. We were interested in developing an animal model of nicotine metabolism that can be used to examine the effects of potential CYP2A6 inhibitors on nicotine metabolism and nicotine-mediated behaviours. Pharmac...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24879 |