An Investigation of Nicotine Metabolism in Mice: The Impact of Pharmacological Inhibition and Genetic Influences on Nicotine Pharmacology

INTRODUCTION: Smoking is one of the single greatest causes of numerous preventable diseases. We were interested in developing an animal model of nicotine metabolism that can be used to examine the effects of potential CYP2A6 inhibitors on nicotine metabolism and nicotine-mediated behaviours. Pharmac...

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Bibliographic Details
Main Author: Siu, Eric C. K.
Other Authors: Tyndale, Rachel
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24879

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