Regulation of Tie2 by Angiopoietin-1 and Angiopoietin-2 in Endothelial Cells

The tyrosine kinase receptor Tie-2 is expressed on the surface of endothelial cells and is necessary for angiogenesis and vascular stability. To date, the best characterized ligands for Tie-2 are Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2). Ang-1 has been identified as the main activating li...

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Bibliographic Details
Main Author: Bogdanovic, Elena
Other Authors: Dumont, Daniel Joseph
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/24476