Modulation of TGF‐β Receptor 1 signalling in Live Cells
TGF-β negatively affects the maintenance and expansion of hematopoietic stem cells ex vivo and its inhibition has been widely studied as a treatment for numerous hematopoietic disorders and cancers. Current inhibitory strategies (small molecule ATP competitors and neutralizing antibodies) are compa...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17505 |