The Effect of a Ketogenic Diet in the Treatment of Succinic Semialdehyde Dehydrogenase Deficiency in Mice

Succinic semialdehyde dehydrogenase (ALDH5A1) deficiency (SSADH-d) is an autosomal recessive, inborn error of gamma-aminobutyric acid (GABA) metabolism that results in psychomotor retardation, ataxia and seizures. A mouse model of SSADH-d (the Aldh5a1-/- mouse) was created to study the pathophysiolo...

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Bibliographic Details
Main Author: Nylen, Kirk
Other Authors: Snead, O. Carter
Format: Others
Language:en_ca
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1807/16811

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