On α-synuclein in the Human Enteric Nervous System

On α-synuclein in the Human Enteric Nervous System

Show other versions (1)

Parkinson’s disease is a neurodegenerative disease resulting primarily from loss of dopaminergic innervation in the striatum subsequent to cell loss in the substantia nigra pars compacta. The abnormal accumulation of the normal pre-synaptic protein α-synuclein (αsyn) forms intraneuronal inclusions k...

Full description

Bibliographic Details
Main Author:	Gray, Madison T.
Language:	en
Published:	2014
Subjects:	α-synuclein alpha-synuclein Parkinson's disease Enteric nervous system vermiform appendix Lewy bodies gastrointestinal
Online Access:	http://hdl.handle.net/10393/30664

Similar Items

On α-synuclein in the Human Enteric Nervous System
by: Gray, Madison T.
Published: (2014)

Initiation and propagation of α-synuclein aggregation in the nervous system
by: Baraa A. Hijaz, et al.
Published: (2020-03-01)

Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve
by: Norihito Uemura, et al.
Published: (2018-05-01)

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology
by: Fredric P. Manfredsson, et al.
Published: (2018-04-01)

Seeding Propensity and Characteristics of Pathogenic αSyn Assemblies in Formalin-Fixed Human Tissue from the Enteric Nervous System, Olfactory Bulb, and Brainstem in Cases Staged for Parkinson’s Disease
by: Alexis Fenyi, et al.
Published: (2021-01-01)

Expression pattern and localization of alpha-synuclein in the human enteric nervous system
by: Martina Böttner, et al.
Published: (2012-12-01)

Amyloid-Beta Peptides Trigger Aggregation of Alpha-Synuclein In Vitro
by: Janett Köppen, et al.
Published: (2020-01-01)

Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models
by: Andreas Weihofen, et al.
Published: (2019-04-01)

Radiosynthesis and in Vivo Evaluation of Two PET Radioligands for Imaging α-Synuclein
by: Xiang Zhang, et al.
Published: (2014-03-01)

α-Synuclein fibril-induced paradoxical structural and functional defects in hippocampal neurons
by: Jessica M. Froula, et al.
Published: (2018-05-01)

Patient-Derived Induced Pluripotent Stem Cells and Organoids for Modeling Alpha Synuclein Propagation in Parkinson's Disease
by: Yong Hui Koh, et al.
Published: (2018-11-01)

Editorial: Biomarkers and Pathogenesis of Alpha-Synuclein in Parkinson's Disease
by: Puyu Li, et al.
Published: (2021-10-01)

Effects of α-synuclein on axonal transport
by: Laura A. Volpicelli-Daley
Published: (2017-09-01)

The Baseline Structure of the Enteric Nervous System and Its Role in Parkinson’s Disease
by: Gianfranco Natale, et al.
Published: (2021-07-01)

Possible Alterations in β-Synuclein, the Non-Amyloidogenic Homologue of α-Synuclein, during Progression of Sporadic α-Synucleinopathies
by: Makoto Hashimoto, et al.
Published: (2012-09-01)

Imaging of α-Synuclein Aggregates in a Rat Model of Parkinson’s Disease Using Raman Microspectroscopy
by: Fide Sevgi, et al.
Published: (2021-09-01)

Alpha-synuclein aggresomes inhibit ciliogenesis and multiple functions of the centrosome
by: Anila Iqbal, et al.
Published: (2020-10-01)

A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease
by: Hélène Pouclet, et al.
Published: (2012-01-01)

Ablating Tau Reduces Hyperexcitability and Moderates Electroencephalographic Slowing in Transgenic Mice Expressing A53T Human α-Synuclein
by: Samuel T. Peters, et al.
Published: (2020-06-01)

Specific immune modulation of experimental colitis drives enteric alpha-synuclein accumulation and triggers age-related Parkinson-like brain pathology
by: Stefan Grathwohl, et al.
Published: (2021-05-01)

Does Parkinson's disease start in the gut?
by: Oscar S. Gershanik

Pathogenic alpha-synuclein aggregates preferentially bind to mitochondria and affect cellular respiration
by: Xinhe Wang, et al.
Published: (2019-03-01)

The Role of Lipids in the Initiation of α-Synuclein Misfolding
by: Martin Kiechle, et al.
Published: (2020-09-01)

The Overcrowded Crossroads: Mitochondria, Alpha-Synuclein, and the Endo-Lysosomal System Interaction in Parkinson’s Disease
by: Kai-Jung Lin, et al.
Published: (2019-10-01)

Alpha-Synuclein in the Gastrointestinal Tract as a Potential Biomarker for Early Detection of Parkinson’s Disease
by: Dominika Fricova, et al.
Published: (2020-11-01)

Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology
by: Nishant N. Vaikath, et al.
Published: (2015-07-01)

Alpha-Synuclein Accumulation and Its Phosphorylation in the Enteric Nervous System of Patients Without Neurodegeneration: An Explorative Study
by: Lu-Lu Bu, et al.
Published: (2020-11-01)

Enteric synucleinopathy: real entity or only a trendy concept?
by: Adrien de Guilhem de Lataillade, et al.
Published: (2020-08-01)

Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression
by: Zachary A. Sorrentino, et al.
Published: (2019-09-01)

Differential effects of immunotherapy with antibodies targeting α-synuclein oligomers and fibrils in a transgenic model of synucleinopathy
by: Omar El-Agnaf, et al.
Published: (2017-08-01)

α-synuclein in the pathophysiology of Alzheimer’s disease
by: Daniel Twohig, et al.
Published: (2019-06-01)

Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology
by: Robert E. Drolet, et al.
Published: (2009-10-01)

Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease
by: Emilio Fernández-Espejo, et al.
Published: (2021-05-01)

Proteolytic α-Synuclein Cleavage in Health and Disease
by: Alexandra Bluhm, et al.
Published: (2021-05-01)

Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies
by: Attems, J., et al.
Published: (2022)

Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC
by: Bradley R. Groveman, et al.
Published: (2018-02-01)

Analysis of α-Synuclein Pathology in PINK1 Knockout Rat Brains
by: Rose B. Creed, et al.
Published: (2019-01-01)

Evaluation of Stp2p-dependent alpha-Synuclein Toxicity in Yeast: Role of GAPDH?
by: Arun George Paul
Published: (2006-01-01)

Studies of α-synuclein Oligomers-with Relevance to Lewy Body Disorders
by: Fagerqvist, Therese
Published: (2013)

Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
by: Michiyo Iba, et al.
Published: (2020-07-01)

Cannot write session to /tmp/vufind_sessions/sess_nujshm38n4t1pi0q2bqc5h3ihb