Control of Uncoupling Protein-1 (UCP1) by Phosphorylation and the Metabolic Impact of Ectopic UCP1 Expression in Skeletal Muscle of Mice
UCP1 is a member of the mitochondrial transmembrane anion carrier protein superfamily and is required to mediate adaptive thermogenesis in brown adipose tissue (BAT). Once activated, UCP1 uncouples mitochondrial respiration from ATP synthesis, thereby wasting the protonmotive force formed across the...
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| Language: | en |
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2013
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| Online Access: | http://hdl.handle.net/10393/24231 |