Enhancing the Oncolytic Efficacy of Vaccinia Virus by Mutagenic Augmentation of EEV Production

Oncolytic viruses are currently under investigation as anti - cancer therapies due to their innate ability to selectively infect and destroy cancer cells. Major barriers to this anti - tumour effect include inefficient viral spread and immune - mediated neutralization. This study aims to overcome th...

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Bibliographic Details
Main Author: Laporte, Aimée N.
Language:en
Published: 2012
Subjects:
EEV
Online Access:http://hdl.handle.net/10393/23348