Modulation of Voltage-Gated Calcium Channels by Group II Metabotropic Glutamate Receptors in the Paraventricular Nucleus of the Thalamus
Compounds that interact with Group II metabotropic glutamate receptors (mGluRs) have antipsychotic effects in animal models. These drugs have also shown efficacy in the treatment of schizophrenia in humans. The mechanism of action is believed to arise from a reduction of glutamatergic transmission i...
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Language: | en |
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2011
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Online Access: | http://hdl.handle.net/10393/19988 |