Dynamic Regulation of Synaptic Transmission onto Serotonin Neurons by Antidepressants

Dynamic Regulation of Synaptic Transmission onto Serotonin Neurons by Antidepressants

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Antidepressants are generally believed to exert their clinical efficacy by enhancing 5-HT transmission. Interestingly, sustained administration of selective serotonin (5-HT) reuptake inhibitors (SSRIs) strongly suppresses in the first few days the firing activity of 5-HT neurons in the dorsal raphe...

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Bibliographic Details
Main Author:	Geddes, Sean D
Language:	en
Published:	2012
Subjects:	Electrophysiology Glutamate NMDAR AMPAR Serotonin SSRI Whole-Cell Recording
Online Access:	http://hdl.handle.net/10393/23532

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