Characterizing Rho Kinase Activity Using a Novel PET Tracer in Hypertrophied Cardiomyocytes

Cardiac hypertrophy is a compensatory response to increased work load or stress on the heart, but over time can lead to heart failure and death. The molecular mechanisms underlying this disease are still not completely understood, however the Rho/Rho kinase pathway has been shown to play a role. N-[...

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Bibliographic Details
Main Author: Moreau, Steven
Language:en
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10393/22887