Mechanisms of Recombinant Heat Shock Protein 27 Atheroprotection: NF-κB Signaling in Macrophages

Mechanisms of Recombinant Heat Shock Protein 27 Atheroprotection: NF-κB Signaling in Macrophages

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The O’Brien lab has demonstrated that Heat shock protein 27 (HSP27)shows attenuated expression in human coronary arteries as the degree of atherosclerosis progresses. Moreover, over-expression of HSP27 reduces atherogenesis in mice. The precise mechanism(s) for HSP27-mediated "atheroprotection&...

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Bibliographic Details
Main Author:	Salari, Samira
Language:	en
Published:	2012
Subjects:	HSP27 NF-κB Atherosclerosis Macrophages IL-10 GM-CSF qRT-PCR arrays THP1 cells
Online Access:	http://hdl.handle.net/10393/20725

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